Steven D Shapiro Selected Research

Pulmonary Emphysema

1/2020	FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema.
3/2014	PPARγ in emphysema: blunts the damage and triggers repair?
12/2004	Accelerated enlargement of experimental abdominal aortic aneurysms in a mouse model of chronic cigarette smoke exposure.
12/2003	Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice.
3/2003	Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.

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Steven D Shapiro Research Topics

Disease

30	Emphysema 01/2022 - 09/2002
22	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 11/2004
17	Inflammation (Inflammations) 01/2022 - 08/2002
16	Neoplasms (Cancer) 10/2021 - 10/2002
9	Lung Neoplasms (Lung Cancer) 01/2021 - 10/2008
5	Pulmonary Emphysema 01/2020 - 03/2003
5	Pneumonia (Pneumonitis) 01/2019 - 06/2004
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2015 - 02/2003
5	Lung Injury 08/2015 - 09/2003
4	Lung Diseases (Lung Disease) 10/2021 - 03/2003
3	Stroke (Strokes) 03/2022 - 08/2005
3	Sepsis (Septicemia) 01/2020 - 09/2014
3	Atherosclerosis 01/2019 - 06/2003
3	Neoplasm Metastasis (Metastasis) 01/2017 - 10/2002
3	Respiratory Insufficiency (Respiratory Failure) 05/2014 - 08/2002
3	Asthma (Bronchial Asthma) 12/2009 - 12/2004
2	Hemorrhage 01/2022 - 08/2006
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 06/2009
2	Infections 12/2016 - 05/2008
2	Bullous Pemphigoid (Pemphigoid) 01/2012 - 09/2006
2	Fibrosis (Cirrhosis) 03/2010 - 01/2007
1	Peripheral Arterial Occlusive Disease 1 05/2022
1	Ischemic Stroke 05/2022
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 03/2022
1	Obesity 01/2022
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022
1	Idiopathic Pulmonary Fibrosis 01/2022
1	Hypokalemia 01/2022
1	Hematoma 01/2022
1	Fever (Fevers) 01/2022
1	Transient Ischemic Attack 04/2021
1	Breast Neoplasms (Breast Cancer) 01/2021

Drug/Important Bio-Agent (IBA)

24	SmokeIBA 01/2022 - 09/2002
14	Matrix Metalloproteinases (MMPs)IBA 01/2018 - 08/2002
11	Peptide Hydrolases (Proteases)FDA Link 01/2017 - 09/2002
8	Leukocyte Elastase (Neutrophil Elastase)IBA 10/2021 - 06/2003
6	Pancreatic Elastase (Elastase)IBA 01/2017 - 12/2003
6	Matrix Metalloproteinase 12IBA 10/2011 - 09/2002
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2010
5	Metalloproteases (Metalloproteinases)IBA 08/2006 - 09/2002
4	Biomarkers (Surrogate Marker)IBA 01/2019 - 03/2009
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 10/2002
4	CytokinesIBA 08/2015 - 06/2003
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2007
3	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021 - 07/2015
3	salicylhydroxamic acid (SHAM)IBA 01/2020 - 09/2014
3	Anti-Bacterial Agents (Antibiotics)IBA 12/2016 - 02/2009
3	Messenger RNA (mRNA)IBA 03/2010 - 10/2002
3	CollagenIBA 01/2010 - 01/2004
3	Matrix Metalloproteinase 8 (Neutrophil Collagenase)IBA 08/2007 - 06/2003
3	Serine Proteases (Serine Protease)IBA 06/2006 - 04/2003
2	Immunoglobulin G (IgG)IBA 10/2021 - 01/2012
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2020 - 12/2016
2	Linezolid (Zyvox)FDA Link 01/2020 - 12/2016
2	LigandsIBA 01/2020 - 01/2017
2	Urethane (Ethyl Carbamate)IBA 01/2020 - 07/2015
2	Pyruvic Acid (Pyruvate)IBA 01/2020 - 12/2016
2	ErbB Receptors (EGF Receptor)IBA 01/2017 - 06/2009
2	Interleukin-6 (Interleukin 6)IBA 08/2015 - 03/2011
2	ChemokinesIBA 08/2015 - 01/2011
2	CarcinogensIBA 07/2015 - 05/2013
2	Receptor for Advanced Glycation End ProductsIBA 01/2015 - 03/2010
2	AutoantibodiesIBA 01/2012 - 09/2006
2	GoldIBA 04/2011 - 10/2008
2	nasIBA 03/2011 - 12/2009
2	Bleomycin (Blenoxane)FDA LinkGeneric 03/2010 - 01/2007
2	EnzymesIBA 07/2009 - 08/2002
2	IntegrinsIBA 08/2006 - 03/2003
2	Matrix Metalloproteinase InhibitorsIBA 06/2006 - 11/2003
2	ElastinIBA 03/2006 - 03/2003
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 11/2005 - 10/2002
1	Mitochondrial DNA (mtDNA)IBA 01/2022
1	Cocaine (Cocaine HCl)IBA 01/2022
1	AntibodiesIBA 10/2021
1	Estrogen ReceptorsIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Dichloroacetic AcidIBA 01/2020
1	DefensinsIBA 01/2020
1	MucinsIBA 01/2020
1	B7-H1 AntigenIBA 01/2020
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2020
1	cecropin AIBA 01/2020
1	Oxidoreductases (Dehydrogenase)IBA 01/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Staphylococcal Protein A (Protein A)IBA 01/2019

Therapy/Procedure

15	Therapeutics 03/2022 - 02/2005
3	Thrombectomy 05/2022 - 01/2022
3	Drug Therapy (Chemotherapy) 11/2019 - 02/2003
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 10/2011 - 02/2003
2	Length of Stay 03/2022 - 01/2020
2	Lung Transplantation 01/2022 - 02/2003
2	Immunotherapy 10/2021 - 01/2020
2	Precision Medicine 09/2014 - 10/2011
1	Minimally Invasive Surgical Procedures 01/2022
1	Long-Term Care 01/2022
1	Ambulatory Care (Outpatient Care) 04/2021
1	Radiotherapy 01/2021
1	Intravenous Administration 01/2020
1	Oncolytic Virotherapy 01/2020